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The antibody against THBS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human THBS2 (NP_003238.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against THBS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human THBS2 (NP_003238.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-12542A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | THBS2 |
| Target Synonyms | TSP2; THBS2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human THBS2 (NP_003238.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P35442 | Immunogen Sequence |
Uniprot Id
P35442
Target Species
Human
Target Name
THBS2
Target Full Name
Thrombospondin-2
Target Function
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
Target Involvement
Intervertebral disc disease (IDD)
Target Protein Families
Thrombospondin family
Target Tissue Specificity
High expression in invertebral disk tissue.
Target Synonyms
THBS2; Thrombospondin-2; TSP2; TSP2_HUMAN
Target Background
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
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