Rabbit anti-Human THRSP Polyclonal Antibody

The antibody against THRSP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human THRSP (NP_003242.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-02614A

Number

Cat.No	ADA-02614A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	THRSP
Target Synonyms	S14; Lpgp; THRP; LPGP1; SPOT14; THRSP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T	Application	ELISA, WB, IF/ICC

Cat.No

ADA-02614A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

THRSP

Target Synonyms

S14; Lpgp; THRP; LPGP1; SPOT14; THRSP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human THRSP (NP_003242.1).	Target Species	Human
Immunogen Sequence	MQVLTKRYPKNCLLTVMDRYAAEVHNMEQVVMIPSLLRDVQLSGPGGQAQAEAPDLYTYFTMLKAICVDVDHGLLPREEWQAKVAGSEENGTAETEEVEDESASGELDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTGQVW	Uniprot ID	Q92748

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human THRSP (NP_003242.1).

Target Species

Human

Immunogen Sequence

MQVLTKRYPKNCLLTVMDRYAAEVHNMEQVVMIPSLLRDVQLSGPGGQAQAEAPDLYTYFTMLKAICVDVDHGLLPREEWQAKVAGSEENGTAETEEVEDESASGELDLEAQFHLHFSSLHHILMHLTEKAQEVTRKYQEMTGQVW

Uniprot ID

Q92748

Background Information

Uniprot Id

Q92748
Target Species

Human
Target Name

THRSP
Target Full Name

Thyroid hormone-inducible hepatic protein
Target Function

Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

SPOT14 family
Target Tissue Specificity

Mainly expressed in tissues that synthesize triglycerides.
Target Research Area

Signal Transduction
Target Synonyms

Lpgp; LPGP1; MGC21659; OTTHUMP00000233866; S14; S14 protein ; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein ; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein ; Thyroid hormone responsive SPOT14 ; Thyroid hormone-inducible hepatic protein
Target Background

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism.

Rabbit anti-Human THRSP Polyclonal Antibody

Specifications

Immunogen Information

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