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Rabbit anti-Human TRIM47 Polyclonal Antibody

The antibody against TRIM47 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-07120A

The antibody against TRIM47 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-07120A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTRIM47
Target SynonymsGOA; RNF100; TRIM47FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse stomachApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 356-530 of human TRIM47 (NP_258411.2).Target SpeciesHuman
Immunogen SequenceELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSUniprot IDQ96LD4
Background Information
  • Uniprot Id

    Q96LD4

  • Target Species

    Human

  • Target Name

    TRIM47

  • Target Full Name

    E3 ubiquitin-protein ligase TRIM47

  • Target Function

    E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    TRIM/RBCC family

  • Target Tissue Specificity

    Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.

  • Target Synonyms

    TRIM47; GOA; RNF100; E3 ubiquitin-protein ligase TRIM47; EC 2.3.2.27; Gene overexpressed in astrocytoma protein; RING finger protein 100; Tripartite motif-containing protein 47

  • Target Background

    Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Located in cytosol.

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