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The antibody against TTC7A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TTC7A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07537A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TTC7A |
| Target Synonyms | TTC7; GIDID; MINAT; TTC7A | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9ULT0 | Immunogen Sequence |
Uniprot Id
Q9ULT0
Target Species
Human
Target Name
TTC7A
Target Full Name
Tetratricopeptide repeat protein 7A
Target Function
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions.
Target Involvement
Gastrointestinal defects and immunodeficiency syndrome (GIDID)
Target Subcellular Location
Cytoplasm. Cell membrane.
Target Tissue Specificity
Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level).
Target Synonyms
TTC7A; KIAA1140; TTC7Tetratricopeptide repeat protein 7A; TPR repeat protein 7A
Target Background
This gene encodes a protein containing tetratricopeptide repeats. Mutations in this gene disrupt intestinal development and can cause early onset inflammatory bowel disease and intestinal atresia. Alternative splicing results in multiple transcript variants.
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