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Rabbit anti-Human UBE2J1 Polyclonal Antibody

The antibody against UBE2J1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2J1 (NP_057105.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-04794A

The antibody against UBE2J1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2J1 (NP_057105.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-04794A ClonalityPolyclonal
Host SpeciesRabbitTarget NameUBE2J1
Target SynonymsUBC6; UBC6E; Ubc6p; CGI-76; NCUBE1; HSPC153; HSPC205; NCUBE-1; HSU93243; UBE2J1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse kidney, Rat lungApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2J1 (NP_057105.2).Target SpeciesHuman
Immunogen SequenceMETRYNLKSPAVKRLMKEAAELKDPTDHYHAQPLEDNLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTANGRFEVGKKICLSISGHHPEUniprot IDQ9Y385
Background Information
  • Uniprot Id

    Q9Y385

  • Target Species

    Human

  • Target Name

    UBE2J1

  • Target Full Name

    Ubiquitin-conjugating enzyme E2 J1

  • Target Function

    Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

  • Target Protein Families

    Ubiquitin-conjugating enzyme family

  • Target Research Area

    Cell Biology

  • Target Synonyms

    UBE2J1; NCUBE1; CGI-76; HSPC153; HSPC205; Ubiquitin-conjugating enzyme E2 J1; EC 2.3.2.23; E2 ubiquitin-conjugating enzyme J1; Non-canonical ubiquitin-conjugating enzyme 1; NCUBE-1; Yeast ubiquitin-conjugating enzyme UBC6 homolog E; HsUBC6e

  • Target Background

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.

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