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The antibody against UBE2J2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against UBE2J2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02574A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBE2J2 |
| Target Synonyms | UBC6; NCUBE2; NCUBE-2; PRO2121; UBE2J2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T, Mouse brain, Mouse testis, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N2K1 | Immunogen Sequence |
Uniprot Id
Q8N2K1
Target Species
Human
Target Name
UBE2J2
Target Full Name
Ubiquitin-conjugating enzyme E2 J2
Target Function
Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Target Protein Families
Ubiquitin-conjugating enzyme family
Target Synonyms
NCUBE-2; NCUBE2; Non-canonical ubiquitin-conjugating enzyme 2; PRO2121; UB2J2_HUMAN; UBC6; UBC6 homolog; ube2j2; Ubiquitin conjugating enzyme 6; Ubiquitin-conjugating enzyme E2 J2; Yeast UBC6 homolog
Target Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
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