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The antibody against UBQLN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against UBQLN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-07025A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UBQLN3 |
| Target Synonyms | TUP-1; UBQLN3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse testis, PC-3, Rat testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 306-620 of human UBQLN3 (NP_059509.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H347 | Immunogen Sequence |
Uniprot Id
Q9H347
Target Species
Human
Target Name
UBQLN3
Target Full Name
Ubiquilin-3
Target Synonyms
TUP1; Ubiquilin 3; Ubiquilin-3; UBQL3_HUMAN; UBQLN3
Target Background
This gene encodes a ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis. It has been suggested that this gene may regulate cell-cycle progression during spermatogenesis, however, it has been shown that the ortholgous mouse gene is dispensable for embryonic development and spermatogenesis.
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