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The antibody against UTY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_009056.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against UTY was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_009056.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01172A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UTY |
| Target Synonyms | UTY1; KDM6C; KDM6AL; UTY | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse liver, Mouse testis, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_009056.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLL | Uniprot ID | O14607 |
Uniprot Id
O14607
Target Species
Human
Target Name
UTY
Target Full Name
Histone demethylase UTY
Target Function
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
Target Subcellular Location
Nucleus.
Target Protein Families
UTX family
Target Synonyms
Histone demethylase UTY; Ubiquitously transcribed TPR protein on the Y chromosome; Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein; Ubiquitously-transcribed TPR protein on the Y chromosome; Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein; UTY; UTY_HUMAN
Target Background
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.
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