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Rabbit anti-Human VPS28 Monoclonal Antibody

The antibody against VPS28 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 122-221 of human VPS28 (Q9UK41) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-14375A

The antibody against VPS28 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 122-221 of human VPS28 (Q9UK41) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-14375A ClonalityMonoclonal
Host SpeciesRabbitTarget NameVPS28
Target SynonymsVPS28; ESCRT-I subunitFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Rat brain, Mouse brain, Mouse lung, Rat kidney, Rat lung, THP-1ApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 122-221 of human VPS28 (Q9UK41).Target SpeciesHuman
Immunogen SequenceKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHAUniprot IDQ9UK41
Background Information
  • Uniprot Id

    Q9UK41

  • Target Species

    Human

  • Target Name

    VPS28

  • Target Full Name

    Vacuolar protein sorting-associated protein 28 homolog

  • Target Function

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process.

  • Target Subcellular Location

    Cell membrane. Late endosome membrane; Peripheral membrane protein.

  • Target Protein Families

    VPS28 family

  • Target Synonyms

    ESCRT-I complex subunit VPS28; H-Vps28; Vacuolar protein sorting 28; Vacuolar protein sorting 28 (yeast); Vacuolar protein sorting 28 homolog (S. cerevisiae); Vacuolar protein sorting 28 homolog; Vacuolar protein sorting-associated protein 28 homolog; VPS 28; Vps28; VPS28_HUMAN; Yeast class E protein Vps28p homolog

  • Target Background

    This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms.

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