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The antibody against WDR6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human WDR6 (NP_060501.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against WDR6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human WDR6 (NP_060501.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WDR6 |
| Target Synonyms | Trm734; WDR6 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | SH-SY5Y | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human WDR6 (NP_060501.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NNW5 | Immunogen Sequence |
Uniprot Id
Q9NNW5
Target Species
Human
Target Name
WDR6
Target Full Name
tRNA (34-2'-O)-methyltransferase regulator WDR6
Target Function
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Target Subcellular Location
Cytoplasm. Note=Colocalizes in the cytoplasm with STK11/LKB1.
Target Protein Families
WD repeat WDR6 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
WDR6; WD repeat-containing protein 6
Target Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms.
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