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Rabbit anti-Human WFDC2 Polyclonal Antibody

The antibody against WFDC2 was raised in rabbit using the Recombinant Human WAP four-disulfide core domain protein 2 protein (31-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-54293A

The antibody against WFDC2 was raised in rabbit using the Recombinant Human WAP four-disulfide core domain protein 2 protein (31-124AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-54293A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWFDC2
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human WAP four-disulfide core domain protein 2 protein (31-124AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ14508
Background Information
  • Uniprot Id

    Q14508

  • Target Species

    Human

  • Target Name

    WFDC2

  • Target Full Name

    WAP four-disulfide core domain protein 2

  • Target Function

    Broad range protease inhibitor.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described

  • Target Synonyms

    HE4; WAP5; EDDM4; dJ461P17.6; HE4/WFDC2

  • Target Background

    This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

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