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Rabbit anti-Human WNT2B Monoclonal Antibody

The antibody against WNT2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human WNT2B (Q93097) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14339A

The antibody against WNT2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human WNT2B (Q93097) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-14339A ClonalityMonoclonal
Host SpeciesRabbitTarget NameWNT2B
Target SynonymsWNT13; WNT2BFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive Samples293T, Mouse brain, Mouse lung, Mouse testis, PC-3, Rat testis, Rat uterus, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human WNT2B (Q93097).Target SpeciesHuman
Immunogen SequenceKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVUniprot IDQ93097
Background Information
  • Uniprot Id

    Q93097

  • Target Species

    Human

  • Target Name

    WNT2B

  • Target Full Name

    Protein Wnt-2b

  • Target Function

    Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Secreted.

  • Target Protein Families

    Wnt family

  • Target Tissue Specificity

    Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidne

  • Target Research Area

    Cancer

  • Target Synonyms

    WNT2B; WNT13; Protein Wnt-2b; Protein Wnt-13

  • Target Background

    This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants.

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