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The antibody against ZCCHC4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-220 of human ZCCHC4 (NP_079212.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZCCHC4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-220 of human ZCCHC4 (NP_079212.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01296A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZCCHC4 |
| Target Synonyms | ZGRF4; HSPC052; ZCCHC4 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 50-220 of human ZCCHC4 (NP_079212.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KVTQGKEETRRFYACSACRDRKDCNFFQWEDEKLSGARLAAREAHNRRCQPPLSRTQCVERYLKFIELPLTQRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQLRRPSQLLYPLENKKTNAQYLFADRSCQFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNIK | Uniprot ID | Q9H5U6 |
Uniprot Id
Q9H5U6
Target Species
Human
Target Name
ZCCHC4
Target Full Name
rRNA N(6)-adenosine-methyltransferase ZCCHC4
Target Function
rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is required for translation.
Target Subcellular Location
Nucleus, nucleolus. Cytoplasm.
Target Synonyms
4930449I23Rik; DHHC domain containing zinc finger protein; HSPC052; MGC21108; OTTMUSP00000027189; zcchc4; ZCHC4_HUMAN; ZGRF4; Zinc finger CCHC domain containing protein 4; Zinc finger CCHC domain-containing protein 4; Zinc finger CCHC type containing 4; Zinc finger GRF type containing 4; Zinc finger, CCHC domain containing 4
Target Background
Enables S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Located in cytoplasm and nucleolus.
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