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Rabbit anti-Human ZDHHC16 Polyclonal Antibody

The antibody against ZDHHC16 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 207-296 of human ZDHHC16 (NP_932162.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02617A

The antibody against ZDHHC16 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 207-296 of human ZDHHC16 (NP_932162.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02617A ClonalityPolyclonal
Host SpeciesRabbitTarget NameZDHHC16
Target SynonymsAPH2; DHHC-16; ZDHHC16FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, HepG2, Mouse brain, Rat lungApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 207-296 of human ZDHHC16 (NP_932162.1).Target SpeciesHuman
Immunogen SequenceHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWEPPPWVTAHSASVMAVUniprot IDQ969W1
Background Information
  • Uniprot Id

    Q969W1

  • Target Species

    Human

  • Target Name

    ZDHHC16

  • Target Full Name

    Palmitoyltransferase ZDHHC16

  • Target Function

    Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization. Also required for eye development. Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function. May play a role in DNA damage response. May be involved in apoptosis regulation. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    DHHC palmitoyltransferase family

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    ZDHHC16; APH2; UNQ2570/PRO6258; Palmitoyltransferase ZDHHC16; Abl-philin 2; Zinc finger DHHC domain-containing protein 16; DHHC-16

  • Target Background

    Enables palmitoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus.

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