Rabbit anti-Human ZDHHC6 Polyclonal Antibody

The antibody against ZDHHC6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 279-413 of human ZDHHC6 (NP_071939.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07197A

Number

Cat.No	ADA-07197A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ZDHHC6
Target Synonyms	DHHC6; DHHC-6; ZNF376; ZDHHC6	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat lung	Application	ELISA, WB

Cat.No

ADA-07197A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ZDHHC6

Target Synonyms

DHHC6; DHHC-6; ZNF376; ZDHHC6

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 279-413 of human ZDHHC6 (NP_071939.1).	Target Species	Human
Immunogen Sequence	SGVPEGDGLEWPVREGCHQYSLTIEQLKQKADKRVRSVRYKVIEDYSGACCPLNKGIKTFFTSPCTEEPRIQLQKGEFILATRGLRYWLYGDKILDDSFIEGVSRIRGWFPRKCVEKCPCDAETDQAPEGEKKNR	Uniprot ID	Q9H6R6

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 279-413 of human ZDHHC6 (NP_071939.1).

Target Species

Human

Immunogen Sequence

SGVPEGDGLEWPVREGCHQYSLTIEQLKQKADKRVRSVRYKVIEDYSGACCPLNKGIKTFFTSPCTEEPRIQLQKGEFILATRGLRYWLYGDKILDDSFIEGVSRIRGWFPRKCVEKCPCDAETDQAPEGEKKNR

Uniprot ID

Q9H6R6

Background Information

Uniprot Id

Q9H6R6
Target Species

Human
Target Name

ZDHHC6
Target Full Name

Palmitoyltransferase ZDHHC6
Target Function

Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC. Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins. Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum. Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Stearoyltransferase that mediates stearoylation of TFRC to inhibit TFRC-mediated activation of the JNK pathway and mitochondrial fragmentation.
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

DHHC palmitoyltransferase family
Target Synonyms

ZDHHC6; ZNF376; Palmitoyltransferase ZDHHC6; Stearoyltransferase ZDHHC6; Transmembrane protein H4; Zinc finger DHHC domain-containing protein 6; DHHC-6; Zinc finger protein 376
Target Background

Enables palmitoyltransferase activity. Involved in positive regulation of mitochondrial fusion and protein palmitoylation. Located in endoplasmic reticulum.

Rabbit anti-Human ZDHHC6 Polyclonal Antibody

Specifications

Immunogen Information

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