Rabbit anti- LMO2 Polyclonal Antibody

The antibody against LMO2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 human LMO2(NP_001135787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08363A

Number

Cat.No	ADA-08363A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	LMO2
Target Synonyms	TTG2; LMO-2; RBTN2; RHOM2; RBTNL1; LMO2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	TF-1	Application	ELISA, WB

Cat.No

ADA-08363A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

LMO2

Target Synonyms

TTG2; LMO-2; RBTN2; RHOM2; RBTNL1; LMO2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

TF-1

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 human LMO2(NP_001135787.1).	Immunogen Sequence	MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKR
Uniprot ID	P25791

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 human LMO2(NP_001135787.1).

Immunogen Sequence

MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKR

Uniprot ID

P25791

Background Information

Uniprot Id

P25791
Target Species

Human
Target Name

LMO2
Target Full Name

Rhombotin-2
Target Function

Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
Target Involvement

A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.
Target Subcellular Location

Nucleus.
Target Synonyms

Cysteine rich protein TTG 2; Cysteine rich protein TTG2; Cysteine-rich protein TTG-2; LIM domain only 2 (rhombotin like 1); LIM domain only 2; LIM domain only protein 2; LMO 2; LMO-2; lmo2; RBTN 2; RBTN L1; RBTN2; RBTN2_HUMAN; RBTNL 1; RBTNL1; RHOM 2; RHOM2; Rhombotin 2; Rhombotin like 1; Rhombotin-2; Rhombotin2; T cell translocation gene 2; T cell translocation protein 2; T-cell translocation protein 2; TTG 2; TTG2
Target Background

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Rabbit anti- LMO2 Polyclonal Antibody

Specifications

Immunogen Information

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