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The antibody against TIM-1/KIM-1/HAVCR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-237 of mouse TIM-1/KIM-1/HAVCR (NP_599009.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TIM-1/KIM-1/HAVCR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-237 of mouse TIM-1/KIM-1/HAVCR (NP_599009.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
Western blot analysis of HuH-7, using TIM-1/KIM-1/HAVCR Rabbit pAb at 1:7000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 180s.
| Cat.No | ADA-08207A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TIM-1/KIM-1/HAVCR |
| Target Synonyms | Tim1; KIM-1; TIM-1; Timd1; TIM-1/KIM-1/HAVCR | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HUH-7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 22-237 of mouse TIM-1/KIM-1/HAVCR (NP_599009.2). | Target Species | Mouse |
|---|---|---|---|
| Uniprot ID | Q5QNS5 | Immunogen Sequence |
Uniprot Id
Q5QNS5
Target Species
Mouse
Target Name
HAVCR1
Target Full Name
Hepatitis A virus cellular receptor 1 homolog
Target Function
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, TIM family
Target Tissue Specificity
Expressed by stimulated T-cells. Expressed during primary antigen stimulation.
Target Synonyms
Tim1; KIM-1; TIM-1; Timd1; TIM-1/KIM-1/HAVCR
Target Background
Enables phosphatidylserine binding activity. Acts upstream of or within positive regulation of mast cell activation; response to lipopolysaccharide; and response to wounding. Located in brush border and cell surface. Is expressed in brain; dorsal aorta; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
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