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Rabbit stau Polyclonal Antibody

The antibody against stau was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) stau protein (321-582aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.

ADC-55381A

The antibody against stau was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) stau protein (321-582aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-55381A ClonalityPolyclonal
Host SpeciesRabbitTarget Namestau
Target SynonymsMaternal effect protein staufen stau CG5753FormLiquid
Species ReactivityDrosophila melanogaster (Fruit fly)IsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification MethodAffinity-chromatography purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Drosophila melanogaster (Fruit fly) stau protein (321-582aa)Target SpeciesDrosophila melanogaster (Fruit fly)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP25159
Background Information
  • Uniprot Id

    P25159

  • Target Species

    Drosophila melanogaster

  • Target Name

    STAU

  • Target Function

    RNA-binding protein which forms ribonucleoprotein complexes (RNPs) that play critical roles in the localization, translational repression and turnover of RNAs during embryogenesis, neurotransmission and neurogenesis. In the oocyte, essential for the localization of both the osk/oskar mRNA to the posterior pole and bcd/bicoid RNA to the anterior pole, and is therefore required for the correct anterior-posterior patterning of the developing embryo. Association with osk or bcd at their respective poles, appears to promote the formation and stabilization of the ribonucleoprotein complexes. Integral component of diverse neuritic ribonucleoprotein complexes (RNPs) that mediate the transport, translation and turnover of neuronal RNAs during neuorgenesis and the translation repression of synaptic transcripts in preparation for their dendritic targeting.

  • Target Subcellular Location

    Cytoplasm, Cytoplasmic ribonucleoprotein granule.

  • Target Tissue Specificity

    Polar granules at the posterior pole of the oocyte, and by the time the egg is laid, at the anterior pole.

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