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Recombinant Human 14-3-3 protein eta (YWHAH), Truncated

Explore the potential of our Recombinant Human YWHAH protein, a critical component in signal transduction research. This protein is a partial variant of the 14-3-3 protein eta (Protein AS1) and is derived from the 4-246aa expression region of the human YWHAH gene. Sourced from E.coli, the protein comes with an N-terminal GST tag to facilitate purification and detection. Presented as a lyophilized powder, this Recombinant Human YWHAH protein boasts a purity of greater than 90% as determined by SDS-PAGE, ensuring reliable performance in your research endeavors.

ACP02298

Explore the potential of our Recombinant Human YWHAH protein, a critical component in signal transduction research. This protein is a partial variant of the 14-3-3 protein eta (Protein AS1) and is derived from the 4-246aa expression region of the human YWHAH gene.
Sourced from E.coli, the protein comes with an N-terminal GST tag to facilitate purification and detection. Presented as a lyophilized powder, this Recombinant Human YWHAH protein boasts a purity of greater than 90% as determined by SDS-PAGE, ensuring reliable performance in your research endeavors.

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Specifications


Cat.No ACP02298 Target NameYWHAH
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range4-246aaMol Weight54.9kDa
Protein LengthPartialPurityGreater than 90% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ04917
Background Information
  • Uniprot Id

    Q04917

  • Target Species

    Human

  • Target Name

    YWHAH

  • Target Full Name

    14-3-3 protein eta

  • Target Function

    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

  • Target Protein Families

    14-3-3 family

  • Target Tissue Specificity

    Expressed mainly in the brain and present in other tissues albeit at lower levels.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    14 3 3 protein eta; 14-3-3 eta; 14-3-3 protein eta; 1433F_HUMAN; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; eta isoform; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide; YWHA 1; YWHA1; Ywhah

  • Target Background

    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.

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