Recombinant Human 39S ribosomal protein L38, mitochondrial (MRPL38)

Uniprot Id

Q96DV4

Target Species

Human

Target Name

MRPL38

Target Full Name

Large ribosomal subunit protein mL38

Target Subcellular Location

Mitochondrion.

Target Protein Families

Phosphatidylethanolamine-binding protein family, Mitochondrion-specific ribosomal protein mL38 subfamily

Target Synonyms

MRPL38; HSPC262; 39S ribosomal protein L38; mitochondrial; L38mt; MRP-L38; Mitochondrial large ribosomal subunit protein mL38

Target Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.