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| Cat.No | ACP20449 | Target Name | RPL27 |
|---|---|---|---|
| Target Synonyms | RPL27; 60S ribosomal protein L27; Large ribosomal subunit protein eL27 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-136aa |
| Mol Weight | 43.1kD | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P61353 |
|---|
Uniprot Id
P61353
Target Species
Human
Target Name
RPL27
Target Full Name
Large ribosomal subunit protein eL27
Target Function
Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs.
Target Involvement
Diamond-Blackfan anemia 16 (DBA16)
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.
Target Protein Families
Eukaryotic ribosomal protein eL27 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
RPL27; 60S ribosomal protein L27; Large ribosomal subunit protein eL27
Target Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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