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Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A)

ACP13866

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13866 Target NameSMPDL3A
Target SynonymsSMPDL3A; ASML3AAcid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; EC 3.1.4.-FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range23-453
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ92484
Background Information
  • Uniprot Id

    Q92484

  • Target Species

    Human

  • Target Name

    SMPDL3A

  • Target Full Name

    Cyclic GMP-AMP phosphodiesterase SMPDL3A

  • Target Function

    Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Acid sphingomyelinase family

  • Target Tissue Specificity

    Detected in blood serum. Detected in macrophages (at protein level).

  • Target Synonyms

    SMPDL3A; ASML3AAcid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; EC 3.1.4.-

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