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| Cat.No | ACP09974 | Target Name | AJAP1 |
|---|---|---|---|
| Target Synonyms | Adherens junction-associated protein 1; Ajap1; AJAP1_HUMAN; Membrane protein shrew-1; MOT8; SHREW-1; SHREW1; Transmembrane protein SHREW1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UKB5 |
|---|
Uniprot Id
Q9UKB5
Target Species
Human
Target Name
AJAP1
Target Full Name
Adherens junction-associated protein 1
Target Function
Plays a role in cell adhesion and cell migration.
Target Subcellular Location
Basolateral cell membrane; Single-pass type III membrane protein. Apical cell membrane; Single-pass type III membrane protein. Cell junction, adherens junction. Note=Mainly basolateral. Localization is mediated by AP1M2.
Target Tissue Specificity
Expressed in uterus and pancreas (at protein level).
Target Synonyms
Adherens junction-associated protein 1; Ajap1; AJAP1_HUMAN; Membrane protein shrew-1; MOT8; SHREW-1; SHREW1; Transmembrane protein SHREW1
Target Background
Enables beta-catenin binding activity. Involved in negative regulation of cell-matrix adhesion; negative regulation of wound healing; and regulation of polarized epithelial cell differentiation. Located in several cellular components, including adherens junction; basolateral plasma membrane; and cell-cell contact zone. Is spanning component of plasma membrane.
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