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| Cat.No | ACP17962 | Target Name | ARFRP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-201 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13795 |
|---|
Uniprot Id
Q13795
Target Species
Human
Target Name
ARFRP1
Target Full Name
ADP-ribosylation factor-related protein 1
Target Function
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network.
Target Protein Families
Small GTPase superfamily, Arf family
Target Tissue Specificity
Found in most tissues.
Target Synonyms
ADP ribosylation factor related protein 1; ADP-ribosylation factor-related protein 1; ARF related protein 1; ARF related protein; ARF-related protein 1; ARFRP_HUMAN; ARFRP1; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein
Target Background
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified.
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