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| Cat.No | ACP22821 | Target Name | AFF2 |
|---|---|---|---|
| Target Synonyms | AF4/FMR2 family member 2; AF4/FMR2 family | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51816 |
|---|
Uniprot Id
P51816
Target Species
Human
Target Name
AFF2
Target Full Name
AF4/FMR2 family member 2
Target Function
RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
Target Involvement
Mental retardation, X-linked, associated with fragile site FRAXE (MRFRAXE)
Target Subcellular Location
Nucleus speckle. Note=When splicing is inhibited, accumulates in enlarged speckles.
Target Protein Families
AF4 family
Target Tissue Specificity
Brain (most abundant in hippocampus and amygdala), placenta and lung.
Target Synonyms
AF4/FMR2 family member 2; AF4/FMR2 family, member 2; AFF2; AFF2_HUMAN; FMR2; FMR2P; Fragile X E mental retardation syndrome protein; fragile X mental retardation 2; Fragile X mental retardation 2 protein; fragile X mental retardation gene associated with FRAXE; FRAXE; mild or borderline mental retardation; MRX2; OTTHUMP00000024204; OX19; Protein FMR-2; Protein Ox19
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