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| Cat.No | ACP16999 | Target Name | ALS2CL |
|---|---|---|---|
| Target Synonyms | AL2CL_HUMAN; ALS2 C-terminal like; ALS2 C-terminal-like protein; Als2cl; DKFZp686I0110; DKFZp686P238; FLJ36525; MGC129698; RN49018 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q60I27 |
|---|
Uniprot Id
Q60I27
Target Species
Human
Target Name
ALS2CL
Target Full Name
ALS2 C-terminal-like protein
Target Function
Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.
Target Subcellular Location
Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.
Target Tissue Specificity
Expressed in heart and kidney.
Target Synonyms
AL2CL_HUMAN; ALS2 C-terminal like; ALS2 C-terminal-like protein; Als2cl; DKFZp686I0110; DKFZp686P238; FLJ36525; MGC129698; RN49018
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