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| Cat.No | ACP23146 | Target Name | AMT |
|---|---|---|---|
| Target Synonyms | Aminomethyltransferase (glycine cleavage system protein T) ; Aminomethyltransferase; AMT; GCE ; GCST ; GCST_HUMAN; GCVT; Glycine cleavage system T protein; mitochondrial; NKH | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 29-403 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P48728 |
|---|
Uniprot Id
P48728
Target Species
Human
Target Name
AMT
Target Full Name
Aminomethyltransferase, mitochondrial
Target Function
The glycine cleavage system catalyzes the degradation of glycine.
Target Involvement
Non-ketotic hyperglycinemia (NKH)
Target Subcellular Location
Mitochondrion.
Target Protein Families
GcvT family
Target Synonyms
Aminomethyltransferase (glycine cleavage system protein T) ; Aminomethyltransferase; AMT; GCE ; GCST ; GCST_HUMAN; GCVT; Glycine cleavage system T protein; mitochondrial; NKH
Target Background
This gene encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene.
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