Home Products Recombinant Human Angiomotin-like protein 1 (AMOTL1), Truncated

Recombinant Human Angiomotin-like protein 1 (AMOTL1), Truncated

ACP15092

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Specifications

Cat.No	ACP15092	Target Name	AMOTL1
Target Synonyms	2310010G08Rik; 2310067L22Rik; 4932416D09Rik; AMOL1_HUMAN; Amotl1; Angiomotin-like protein 1; FLJ00155; JEAP; Junction enriched and associated protein; mFLJ00155	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IY63

Background Information

Uniprot Id

Q8IY63
Target Species

Human
Target Name

AMOTL1
Target Full Name

Angiomotin-like protein 1
Target Function

Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Target Subcellular Location

Cell junction, tight junction.
Target Protein Families

Angiomotin family
Target Synonyms

2310010G08Rik; 2310067L22Rik; 4932416D09Rik; AMOL1_HUMAN; Amotl1; Angiomotin-like protein 1; FLJ00155; JEAP; Junction enriched and associated protein; mFLJ00155
Target Background

The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Angiomotin-like protein 1 (AMOTL1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Angiomotin-like protein 1 (AMOTL1), Truncated Now

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