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Recombinant Human Angiopoietin-like protein 8 (ANGPTL8)

Introducing our Recombinant Human C19orf80 (ANGPTL8), an outstanding research tool for scientists investigating cell biology, lipid metabolism, and angiogenesis. Angiopoietin-like protein 8, also known as Betatrophin, Lipasin, or Refeeding-induced fat and liver protein, is a secreted protein with essential roles in lipid metabolism and glucose homeostasis, making it a potential target for diabetes and obesity research. Our Recombinant Human ANGPTL8 is derived from E.coli expression systems and represents the full length of the mature protein, spanning the 22-198 amino acid expression region. The protein is N-terminal 6xHis-tagged for convenient purification and detection processes. Boasting a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human C19orf80 (ANGPTL8) provides consistent quality and performance in your experiments. This product is available in both liquid and lyophilized powder forms to accommodate a variety of research needs.

ACP04263

Introducing our Recombinant Human C19orf80 (ANGPTL8), an outstanding research tool for scientists investigating cell biology, lipid metabolism, and angiogenesis. Angiopoietin-like protein 8, also known as Betatrophin, Lipasin, or Refeeding-induced fat and liver protein, is a secreted protein with essential roles in lipid metabolism and glucose homeostasis, making it a potential target for diabetes and obesity research.
Our Recombinant Human ANGPTL8 is derived from E.coli expression systems and represents the full length of the mature protein, spanning the 22-198 amino acid expression region. The protein is N-terminal 6xHis-tagged for convenient purification and detection processes. Boasting a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human C19orf80 (ANGPTL8) provides consistent quality and performance in your experiments. This product is available in both liquid and lyophilized powder forms to accommodate a variety of research needs.

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Specifications


Cat.No ACP04263 Target NameC19orf80
Target SynonymsANGPTL8; C19orf80; RIFL; UNQ599/PRO1185Angiopoietin-like protein 8; Betatrophin; Lipasin; Refeeding-induced fat and liver proteinFormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range22-198aa
Mol Weight23.9kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6UXH0
Background Information
  • Uniprot Id

    Q6UXH0

  • Target Species

    Human

  • Target Name

    ANGPTL8

  • Target Full Name

    Angiopoietin-like protein 8

  • Target Function

    Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state.

  • Target Involvement

    Diabetes mellitus, insulin-dependent (IDDM); Diabetes mellitus, non-insulin-dependent (NIDDM)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    ANGPTL8 family

  • Target Tissue Specificity

    Predominantly expressed in liver. Also expressed in adipose tissues.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185Angiopoietin-like protein 8; Betatrophin; Lipasin; Refeeding-induced fat and liver protein

  • Target Background

    Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.

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