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Recombinant Human Anoctamin-2 (ANO2), Truncated

ACP05678

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Specifications

Cat.No	ACP05678	Target Name	ANO2
Target Synonyms	Ano2; ANO2_HUMAN; Anoctamin 2; Anoctamin-2; C12orf3; Chromosome 12 open reading frame 3; DKFZp434P102; Transmembrane protein 16B (eight membrane-spanning domains); Transmembrane protein 16B	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NQ90

Background Information

Uniprot Id

Q9NQ90
Target Species

Human
Target Name

ANO2
Target Full Name

Anoctamin-2
Target Function

Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

Anoctamin family
Target Tissue Specificity

Retina, especially in the photoreceptor synaptic terminals.
Target Synonyms

Ano2; ANO2_HUMAN; Anoctamin 2; Anoctamin-2; C12orf3; Chromosome 12 open reading frame 3; DKFZp434P102; Transmembrane protein 16B (eight membrane-spanning domains); Transmembrane protein 16B
Target Background

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).

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Recombinant Human Anoctamin-2 (ANO2), Truncated

Specifications

Immunogen Information

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