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| Cat.No | ACP12875 | Target Name | AIFM3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-605 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96NN9 |
|---|
Uniprot Id
Q96NN9
Target Species
Human
Target Name
AIFM3
Target Full Name
Apoptosis-inducing factor 3
Target Function
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Target Subcellular Location
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Target Protein Families
FAD-dependent oxidoreductase family
Target Tissue Specificity
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Target Synonyms
AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor; mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137
Target Background
Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; flavin adenine dinucleotide binding activity; and metal ion binding activity. Involved in execution phase of apoptosis. Located in cytosol; endoplasmic reticulum; and mitochondrial inner membrane.
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