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Recombinant Human Aquaporin-1 (AQP1), Truncated

ACP09284

Number
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Specifications


Cat.No ACP09284 Target NameAQP1
Target SynonymsAQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubuleFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Mol Weight21.6kD
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP29972
Background Information
  • Uniprot Id

    P29972

  • Target Species

    Human

  • Target Name

    AQP1

  • Target Full Name

    Aquaporin-1

  • Target Function

    Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    MIP/aquaporin (TC 1.A.8) family

  • Target Tissue Specificity

    Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.

  • Target Research Area

    Transport

  • Target Synonyms

    AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule

  • Target Background

    This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement.

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