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| Cat.No | ACP17835 | Target Name | ACAP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-740 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q15027 |
|---|
Uniprot Id
Q15027
Target Species
Human
Target Name
ACAP1
Target Full Name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Target Function
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Target Subcellular Location
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
Target Synonyms
ACAP 1; ACAP1; ACAP1_HUMAN; Arf GAP with coiled coil ANK repeat and PH domains 1; Arf GAP with coiled coil; ankyrin repeat; and pleckstrin homology domains 1; Arf-GAP with coiled-coil; ANK repeat and PH domain-containing protein 1; ArfGAP with coiled-coil; ankyrin repeat and PH domains 1; CENT B1; Centaurin beta 1; Centaurin-beta-1; CENTB 1; Cnt b1; Cnt-b1; Cntb1; KIAA0050
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