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Recombinant Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (ACAP1)

ACP17835

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17835 Target NameACAP1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-740Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ15027
Background Information
  • Uniprot Id

    Q15027

  • Target Species

    Human

  • Target Name

    ACAP1

  • Target Full Name

    Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

  • Target Function

    GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.

  • Target Subcellular Location

    Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Tissue Specificity

    Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.

  • Target Synonyms

    ACAP 1; ACAP1; ACAP1_HUMAN; Arf GAP with coiled coil ANK repeat and PH domains 1; Arf GAP with coiled coil; ankyrin repeat; and pleckstrin homology domains 1; Arf-GAP with coiled-coil; ANK repeat and PH domain-containing protein 1; ArfGAP with coiled-coil; ankyrin repeat and PH domains 1; CENT B1; Centaurin beta 1; Centaurin-beta-1; CENTB 1; Cnt b1; Cnt-b1; Cntb1; KIAA0050

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