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| Cat.No | ACP19228 | Target Name | ATPAF2 |
|---|---|---|---|
| Target Synonyms | ATPAF2; ATP12; LP3663ATP synthase mitochondrial F1 complex assembly factor 2; ATP12 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 41-289 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N5M1 |
|---|
Uniprot Id
Q8N5M1
Target Species
Human
Target Name
ATPAF2
Target Full Name
ATP synthase mitochondrial F1 complex assembly factor 2
Target Function
May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).
Target Involvement
Mitochondrial complex V deficiency, nuclear 1 (MC5DN1)
Target Subcellular Location
Mitochondrion.
Target Protein Families
ATP12 family
Target Tissue Specificity
Widely expressed.
Target Research Area
Metabolism
Target Synonyms
ATPAF2; ATP12; LP3663ATP synthase mitochondrial F1 complex assembly factor 2; ATP12 homolog
Target Background
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. This gene is located within the Smith-Magenis syndrome region on chromosome 17. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.
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