Recombinant Human ATP synthase subunit epsilon-like protein, mitochondrial (ATP5EP2)

Uniprot Id

Q5VTU8

Target Species

Human

Target Name

ATP5F1EP2

Target Full Name

ATP synthase subunit epsilon-like protein, mitochondrial

Target Function

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits

Target Subcellular Location

Mitochondrion inner membrane.

Target Protein Families

Eukaryotic ATPase epsilon family

Target Synonyms

ATP5F1EP2; ATP5EP2ATP synthase subunit epsilon-like protein; mitochondrial; ATP synthase F1 subunit epsilon pseudogene 2