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Recombinant Human Bcl-2-associated transcription factor 1 (BCLAF1), Truncated

ACP10235

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10235 Target NameBCLAF1
Target SynonymsBcl 2 associated transcription factor; Bcl-2-associated transcription factor 1; BCL2 associated transcription factor 1; BCLAF1; BCLF1_HUMAN; bK211L9.1; Btf; KIAA0164FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NYF8
Background Information
  • Uniprot Id

    Q9NYF8

  • Target Species

    Human

  • Target Name

    BCLAF1

  • Target Full Name

    Bcl-2-associated transcription factor 1

  • Target Function

    Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Nucleus speckle. Nucleus, nucleoplasm.

  • Target Protein Families

    BCLAF1/THRAP3 family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    Bcl 2 associated transcription factor; Bcl-2-associated transcription factor 1; BCL2 associated transcription factor 1; BCLAF1; BCLF1_HUMAN; bK211L9.1; Btf; KIAA0164

  • Target Background

    This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

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