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| Cat.No | ACP13767 | Target Name | CARD19 |
|---|---|---|---|
| Target Synonyms | Bcl10 interacting protein with CARD protein; Bcl10-interacting CARD protein; BINCA_HUMAN; BinCARD; C9orf89; Chromosome 9 open reading frame 89 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-228 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96LW7 |
|---|
Uniprot Id
Q96LW7
Target Species
Human
Target Name
CARD19
Target Full Name
Caspase recruitment domain-containing protein 19
Target Function
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Target Subcellular Location
[Isoform 1]: Nucleus. Note=Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Target Tissue Specificity
Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
Target Synonyms
Bcl10 interacting protein with CARD protein; Bcl10-interacting CARD protein; BINCA_HUMAN; BinCARD; C9orf89; Chromosome 9 open reading frame 89
Target Background
Located in mitochondrion.
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