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| Cat.No | ACP11659 | Target Name | B4GALT6 |
|---|---|---|---|
| Target Synonyms | 4- galactosyltransferase; polypeptide 6; UDP-Gal:glucosylceramide beta-1; UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase 6, 4-galactosyltransferase 6; 4-galactosyltransferase; 4-GalTase 6; AA536803; AU022389; b4Gal-T6; B4galt6; B4GT6_HUMAN; Beta-1; beta-1, 4-galactosyltransferase 6; beta-1, 4-galactosyltransferase 6; UDP-Gal:betaGlcNAc beta 1, 4-galactosyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1, 4-GalTase 6; Beta4Gal-T6; beta4GalT-VI; LacCer synthase; Lactosylceramide synthase; UDP-Gal:beta-GlcNAc beta-1; UDP-Gal:beta-GlcNAc beta-1 | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UBX8 |
|---|
Uniprot Id
Q9UBX8
Target Species
Human
Target Name
B4GALT6
Target Full Name
Beta-1,4-galactosyltransferase 6
Target Function
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation.
Target Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 7 family
Target Tissue Specificity
High expression in brain and adrenal gland, lower in liver, lung, colon and peripheral white blood cells.
Target Synonyms
4-galactosyltransferase 6; 4-galactosyltransferase; 4-GalTase 6; AA536803; AU022389; b4Gal-T6; B4galt6; B4GT6_HUMAN; Beta-1; beta-1,4-galactosyltransferase 6; beta-1,4-GalTase 6; Beta4Gal-T6; beta4GalT-VI; LacCer synthase; Lactosylceramide synthase; UDP-Gal:beta-GlcNAc beta-1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase; polypeptide 6; UDP-Gal:glucosylceramide beta-1; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6
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