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Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (NDST3), Truncated

ACP20805

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP20805	Target Name	NDST3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95803

Background Information

Uniprot Id

O95803
Target Species

Human
Target Name

NDST3
Target Full Name

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3
Target Function

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity.
Target Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families

Sulfotransferase 1 family, NDST subfamily
Target Tissue Specificity

Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle.
Target Synonyms

NDST3; HSST3; UNQ2544/PRO4998Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; EC 2.8.2.8; Glucosaminyl N-deacetylase/N-sulfotransferase 3; NDST-3; hNDST-3; N-heparan sulfate sulfotransferase 3; N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3; EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3; EC 2.8.2.-)]

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Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (NDST3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (NDST3), Truncated Now

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