Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP24193 | Target Name | MTHFD2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 36-350 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P13995 |
|---|
Uniprot Id
P13995
Target Species
Human
Target Name
MTHFD2
Target Full Name
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Target Function
Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Tetrahydrofolate dehydrogenase/cyclohydrolase family
Target Synonyms
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase; mitochondrial; Descriptions; Methenyltetrahydrofolate cyclohydrolase; methylene tetrahydrofolate dehydrogenase (NAD+ dependent); methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent); methylenetetrahydrofolate dehydrogenase 2; MGC82516; MTDC_HUMAN; MTHFD2; mthfd2 methylene tetrahydrofolate dehydrogenase (NAD+ dependent); NAD-dependent methylene tetrahydrofolate dehydrogenase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC
Target Background
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
