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| Cat.No | ACP16339 | Target Name | BLOC1S3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-202 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6QNY0 |
|---|
Uniprot Id
Q6QNY0
Target Species
Human
Target Name
BLOC1S3
Target Full Name
Biogenesis of lysosome-related organelles complex 1 subunit 3
Target Function
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Target Involvement
Hermansky-Pudlak syndrome 8 (HPS8)
Target Subcellular Location
Cytoplasm.
Target Protein Families
BLOC1S3 family
Target Synonyms
Biogenesis of lysosomal organelles complex 1 subunit 3; Biogenesis of lysosome-related organelles complex 1 subunit 3; BL1S3_HUMAN; BLOC-1 subunit 3; Bloc1s3; BLOS3; HPS8; reduced pigmentation; mouse; homolog of; RP
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