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Recombinant Human Bridging integrator 3 (BIN3)

ACP18990

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18990 Target NameBIN3
Target SynonymsBIN3Bridging integrator 3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-253
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NQY0
Background Information
  • Uniprot Id

    Q9NQY0

  • Target Species

    Human

  • Target Name

    BIN3

  • Target Full Name

    Bridging integrator 3

  • Target Function

    Involved in cytokinesis and septation where it has a role in the localization of F-actin.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton.

  • Target Tissue Specificity

    Ubiquitously expressed except in brain.

  • Target Synonyms

    BIN3Bridging integrator 3

  • Target Background

    The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.

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