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| Cat.No | ACP18286 | Target Name | BTN1A1 |
|---|---|---|---|
| Target Synonyms | BT; BT1A1_HUMAN; BTN; BTN1; Btn1a1; butyrophilin; Butyrophilin subfamily 1 member A1; butyrophilin; subfamily 1; member A1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13410 |
|---|
Uniprot Id
Q13410
Target Species
Human
Target Name
BTN1A1
Target Full Name
Butyrophilin subfamily 1 member A1
Target Function
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Secreted.
Target Protein Families
Immunoglobulin superfamily, BTN/MOG family
Target Synonyms
BT; BT1A1_HUMAN; BTN; BTN1; Btn1a1; butyrophilin; Butyrophilin subfamily 1 member A1; butyrophilin; subfamily 1; member A1
Target Background
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families
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