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| Cat.No | ACP08138 | Target Name | CALHM3 |
|---|---|---|---|
| Target Synonyms | CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86XJ0 |
|---|
Uniprot Id
Q86XJ0
Target Species
Human
Target Name
CALHM3
Target Full Name
Calcium homeostasis modulator protein 3
Target Function
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Target Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
CALHM family
Target Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Target Synonyms
CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A
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