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Recombinant Human Cap-specific mRNA (nucleoside-2′-O-)-methyltransferase 1 (FTSJD2), Truncated

ACP13424

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13424 Target NameCMTR1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N1G2
Background Information
  • Uniprot Id

    Q8N1G2

  • Target Species

    Human

  • Target Name

    CMTR1

  • Target Full Name

    Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

  • Target Function

    S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1; Cap1 2''O-ribose methyltransferase 1; CMTR1; CMTR1_HUMAN; FLJ22156; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; FTSJD 2; hMTr1; Interferon-stimulated gene 95 kDa protein; ISG95; KIAA0082; MTr1; OTTHUMP00000016324; Uncharacterized protein KIAA0082

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