Recombinant Human Caprin-1 (CAPRIN1), Truncated

Uniprot Id

Q14444

Target Species

Human

Target Name

CAPRIN1

Target Full Name

Caprin-1

Target Function

May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Target Subcellular Location

Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, lamellipodium.

Target Protein Families

Caprin family

Target Tissue Specificity

Ubiquitous.

Target Research Area

Others

Target Synonyms

activation/proliferation-associated protein 1; CAPR1_HUMAN; Caprin-1; CAPRIN1; Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; GPIAP1; GPIP137; M11S1; Membrane component chromosome 11 surface marker 1; p137GPI; RNA granule protein 105; RNG105

Target Background

Enables RNA binding activity. Predicted to be involved in negative regulation of translation and positive regulation of dendritic spine morphogenesis. Located in cell leading edge and cytosol.