Recombinant Human Carbonic anhydrase 3 (CA3)

Uniprot Id

P07451

Target Species

Human

Target Name

CA3

Target Full Name

Carbonic anhydrase 3

Target Function

Reversible hydration of carbon dioxide.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Alpha-carbonic anhydrase family

Target Tissue Specificity

Muscle specific.

Target Synonyms

CA III ; CA-III; Ca3; CAH3_HUMAN; CAIII ; Car3 ; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; Carbonic anhydrase III muscle specific; EC 4.2.1.1; Epididymis secretory sperm binding protein Li 167mP; HEL S 167mP

Target Background

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.