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| Cat.No | ACP13711 | Target Name | CMYA5 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N3K9 |
|---|
Uniprot Id
Q8N3K9
Target Species
Human
Target Name
CMYA5
Target Full Name
Cardiomyopathy-associated protein 5
Target Function
May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A. May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration. Plays a role in the assembly of ryanodine receptor (RYR2) clusters in striated muscle.
Target Subcellular Location
Nucleus. Sarcoplasmic reticulum. Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, myofibril, sarcomere, M line.
Target Tissue Specificity
Expressed in skeletal muscle; at a strong level and in heart.
Target Synonyms
2310076E16Rik; C5orf10; Cardiomyopathy associated 5; Cardiomyopathy associated protein 5; Cardiomyopathy-associated protein 5; Chromosome 5 open reading frame 10; CMYA 5; Cmya5; CMYA5_HUMAN; DKFZp451G182; DKFZp451G223; DTNBP2; Dystrobrevin binding protein 2; Dystrobrevin-binding protein 2; Genethonin 3; Genethonin-3; Myospryn; SPRY domain containing protein 2; SPRY domain-containing protein 2; SPRYD2; TRIM76; Tripartite motif containing 76; Tripartite motif containing protein 76; Tripartite motif-containing protein 76
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