Recombinant Human Cathelicidin antimicrobial peptide (CAMP)

Uniprot Id

P49913

Target Species

Human

Target Name

CAMP

Target Full Name

Cathelicidin antimicrobial peptide

Target Function

Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.

Target Subcellular Location

Secreted.

Target Protein Families

Cathelicidin family

Target Tissue Specificity

Expressed in bone marrow and testis and neutrophils.

Target Research Area

others

Target Synonyms

18 kDa cationic antimicrobial protein; Antibacterial peptide LL-37; Antibacterial protein FALL-39; CAMP; CAMP_HUMAN; CAP 18; CAP-18; CAP18; Cathelicidin antimicrobial peptide; Cathelin-like protein; Cathelin-related antimicrobial peptide; CATHL3; Cationic antimicrobial protein; 18-KD; CLP; Cnlp; Cramp; CRAMP; mouse; homolog of; FALL 39 ; FALL-39 peptide antibiotic; FALL39 ; hCAP 18; hCAP-18; hCAP18; HSD26 ; LL37; MCLP; Peptide antibiotic; PR-39; porcine; homolog of

Target Background

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation.