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| Cat.No | ACP00640 | Target Name | CCNA2&CDK2 |
|---|---|---|---|
| Target Synonyms | Cyclin-A&Cell division protein kinase 2;p33 protein kinase | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Expression Range | 1-432aa&1-298aa |
| Mol Weight | 77.9 kDa&35.3 kDa | Protein Length | Heterodimer |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20248 P24941 |
|---|
Uniprot Id
P20248
Target Species
Human
Target Name
CCNA2
Target Full Name
Cyclin-A2
Target Function
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Cyclin family, Cyclin AB subfamily
Target Research Area
Cancer
Target Synonyms
CCN1; CCNA; Ccna2; CCNA2_HUMAN; Cyclin A2; Cyclin-A; Cyclin-A2
Target Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M.
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